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HBV Target gene Detail Information

> MASP1 Gene Search Result


Gene Information
Gene Name MASP1
Gene ID 5648
Gene Full Name mannan binding lectin serine peptidase 1
Gene Alias 3MC1; MAP1; MASP; RaRF; CRARF; MASP3; MAp44; PRSS5; CRARF1
Transcripts ENSG00000127241
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;Predicted to be secreted;
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P48740
HGNC ID HGNC:6901
VEGA ID OTTHUMG00000156461
OMIM ID 600521
String ID 9606.ENSP00000296280
PharmGKB ID PA30644
Target gene [MASP1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1010259 chr3 12 1 13 View
1010260 chr3 13 13 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of MASP1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
MASP1 expression: Low -> High
Lollipop of MASP1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of MASP1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MASP1 expression and immune infiltrating cell level correlation result in HBV+ samples
MASP1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).