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HTLV1 Target gene Detail Information

> MARVELD2 Gene Search Result


Gene Information
Gene Name MARVELD2
Gene ID 153562
Gene Full Name MARVEL domain containing 2
Gene Alias Tric; DFNB49; MARVD2; MRVLDC2
Transcripts ENSG00000274671
Virus HTLV1
Gene Type protein coding
HPA Location Info Cell Junctions;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID Q8N4S9
HGNC ID HGNC:26401
VEGA ID OTTHUMG00000175329
OMIM ID 610572
String ID 9606.ENSP00000323264
PharmGKB ID PA134954584
Target gene [MARVELD2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6001064 chr5 419 153 35 607 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of MARVELD2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MARVELD2 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of MARVELD2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MARVELD2 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of MARVELD2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MARVELD2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).