HIV Target gene Detail Information

> MARK4 Gene Search Result

Gene Information

Gene Name	MARK4
Gene ID	57787
Gene Full Name	microtubule affinity regulating kinase 4
Gene Alias	MARK4L; MARK4S; MARKL1; PAR-1D; MARKL1L
Transcripts	ENSG00000007047
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q96L34
HGNC ID	HGNC:13538
VEGA ID	OTTHUMG00000181769
OMIM ID	606495
String ID	9606.ENSP00000262891
Drugbank ID	BE0009436
PharmGKB ID	PA30641

Target gene [MARK4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4015735	chr19	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MARK4 expression and immune infiltrating cell level correlation result in HIV+ samples
MARK4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).