HIV Target gene Detail Information

> MARK2 Gene Search Result

Gene Information

Gene Name	MARK2
Gene ID	2011
Gene Full Name	microtubule affinity regulating kinase 2
Gene Alias	EMK1; EMK-1; PAR-1; Par1b; Par-1b
Transcripts	ENSG00000072518
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q7KZI7
HGNC ID	HGNC:3332
VEGA ID	OTTHUMG00000160504
OMIM ID	600526
String ID	9606.ENSP00000385751
Drugbank ID	BE0009434
PharmGKB ID	PA35047

Target gene [MARK2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000223	chr11	352	253	94	699	View
4000401	chr11	32	260	199	491	View
4002174	chr11	76	7	25	108	View
4002809	chr11	79			79	View
4003578	chr11	31	25	2	58	View
4004514	chr11	32	2	9	43	View
4005450	chr11	31		1	32	View
4005688	chr11	30			30	View
4005732	chr11	5	12	13	30	View
4007395	chr11	7	2	10	19	View
4009518	chr11	10	1		11	View
4009642	chr11	3	5	3	11	View
4010173	chr11	8	1		9	View
4015736	chr11		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MARK2 expression and immune infiltrating cell level correlation result in HIV+ samples
MARK2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MARK2 expression and immune infiltrating cell level correlation result in HIV+ samples
MARK2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).