HBV Target gene Detail Information

> MARK1 Gene Search Result

Gene Information

Gene Name	MARK1
Gene ID	4139
Gene Full Name	microtubule affinity regulating kinase 1
Gene Alias	MARK; Par1c; Par-1c
Transcripts	ENSG00000116141
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q9P0L2
HGNC ID	HGNC:6896
VEGA ID	OTTHUMG00000037351
OMIM ID	606511
String ID	9606.ENSP00000483424
Drugbank ID	BE0009433
PharmGKB ID	PA30639

Target gene [MARK1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006704	chr1	9	24	2	35	View
1006790	chr1	9	23	2	34	View
1010091	chr1	9	4		13	View
1018789	chr1				0	View
1404679	chr1	24	8		32	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of MARK1 expression and immune infiltrating cell level correlation result in HBV+ samples
MARK1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).