HIV Target gene Detail Information

> MAPRE1 Gene Search Result

Gene Information

Gene Name	MAPRE1
Gene ID	22919
Gene Full Name	microtubule associated protein RP/EB family member 1
Gene Alias	EB1
Transcripts	ENSG00000101367
Virus	HIV
Gene Type	protein coding
HPA Location Info	Centriolar satellite;Cytosol;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q15691
HGNC ID	HGNC:6890
VEGA ID	OTTHUMG00000032228
OMIM ID	603108
String ID	9606.ENSP00000364721
PharmGKB ID	PA30634

Target gene [MAPRE1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002704	chr20	83			83	View
4004936	chr20	11	27		38	View
4009687	chr20	9	2		11	View
4012478	chr20	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MAPRE1 expression and immune infiltrating cell level correlation result in HIV+ samples
MAPRE1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MAPRE1 expression and immune infiltrating cell level correlation result in HIV+ samples
MAPRE1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).