HIV Target gene Detail Information

> MAPK8IP3 Gene Search Result

Gene Information

Gene Name	MAPK8IP3
Gene ID	23162
Gene Full Name	mitogen-activated protein kinase 8 interacting protein 3
Gene Alias	syd; JIP3; SYD2; JIP-3; JSAP1
Transcripts	ENSG00000138834
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9UPT6
HGNC ID	HGNC:6884
VEGA ID	OTTHUMG00000128637
OMIM ID	605431
String ID	9606.ENSP00000250894
PharmGKB ID	PA30628

Target gene [MAPK8IP3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000240	chr16	299	193	168	660	View
4006844	chr16	21	1		22	View
4008933	chr16	3	5	5	13	View
4009916	chr16	4	4	2	10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MAPK8IP3 expression and immune infiltrating cell level correlation result in HIV+ samples
MAPK8IP3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MAPK8IP3 expression and immune infiltrating cell level correlation result in HIV+ samples
MAPK8IP3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).