HBV Target gene Detail Information

> MAPK4 Gene Search Result

Gene Information

Gene Name	MAPK4
Gene ID	5596
Gene Full Name	mitogen-activated protein kinase 4
Gene Alias	ERK4; ERK-4; PRKM4; p63MAPK; p63-MAPK
Transcripts	ENSG00000282110
Virus	HBV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Nucleoplasm;Midbody;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P31152
HGNC ID	HGNC:6878
VEGA ID	OTTHUMG00000191323
OMIM ID	176949
String ID	9606.ENSP00000383234
Drugbank ID	BE0009430; BE0009853
PharmGKB ID	PA30623

Target gene [MAPK4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008048	chr18	15	3	4	22	View
1012345	chr18	1	1	5	7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of MAPK4 expression and immune infiltrating cell level correlation result in HBV+ samples
MAPK4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).