HTLV1 Target gene Detail Information

> MAPK13 Gene Search Result

Gene Information

Gene Name	MAPK13
Gene ID	5603
Gene Full Name	mitogen-activated protein kinase 13
Gene Alias	SAPK4; PRKM13; MAPK 13; MAPK-13; p38delta
Transcripts	ENSG00000156711
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoli;Nucleoli rim;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	O15264
HGNC ID	HGNC:6875
VEGA ID	OTTHUMG00000014587
OMIM ID	602899
String ID	9606.ENSP00000211287
Drugbank ID	BE0003391; BE0009853
PharmGKB ID	PA30620

Target gene [MAPK13] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6008069	chr6	18	12	19	49	View
6008070	chr6	18	12	19	49	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of MAPK13 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MAPK13 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of MAPK13 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MAPK13 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of MAPK13 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MAPK13 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).