HBV Target gene Detail Information

> MAPK10 Gene Search Result

Gene Information

Gene Name	MAPK10
Gene ID	5602
Gene Full Name	mitogen-activated protein kinase 10
Gene Alias	JNK3; JNK3A; PRKM10; SAPK1b; p493F12; p54bSAPK
Transcripts	ENSG00000109339
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins
Gene Function	Suppressor gene
Uniport_ID	P53779
HGNC ID	HGNC:6872
VEGA ID	OTTHUMG00000130604
OMIM ID	602897
String ID	9606.ENSP00000352157
Drugbank ID	BE0001097; BE0009865; BE0009853
PharmGKB ID	PA30617

Target gene [MAPK10] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009848	chr4	12	2		14	View
1018617	chr4				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of MAPK10 expression and immune infiltrating cell level correlation result in HBV+ samples
MAPK10 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).