HPV Target gene Detail Information

> MAP3K15 Gene Search Result

Gene Information

Gene Name	MAP3K15
Gene ID	389840
Gene Full Name	mitogen-activated protein kinase kinase kinase 15
Gene Alias	ASK3; bA723P2.3
Transcripts	ENSG00000180815
Virus	HPV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q6ZN16
HGNC ID	HGNC:31689
VEGA ID	OTTHUMG00000022724
OMIM ID	300820
String ID	9606.ENSP00000345629
Drugbank ID	BE0009420
PharmGKB ID	PA134935369

Target gene [MAP3K15] related to VISs

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DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5402310	chrX	1	6		7	View

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Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of MAP3K15 expression and immune infiltrating cell level correlation result in HPV+ samples
MAP3K15 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).

> Dataset: HNSC