HIV Target gene Detail Information

> MAP2K6 Gene Search Result

Gene Information

Gene Name	MAP2K6
Gene ID	5608
Gene Full Name	mitogen-activated protein kinase kinase 6
Gene Alias	MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; SAPKK-3
Transcripts	ENSG00000108984
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	P52564
HGNC ID	HGNC:6846
VEGA ID	OTTHUMG00000180311
OMIM ID	601254
String ID	9606.ENSP00000468348
Drugbank ID	BE0009415
PharmGKB ID	PA30591

Target gene [MAP2K6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002631	chr17	26	30	30	86	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MAP2K6 expression and immune infiltrating cell level correlation result in HIV+ samples
MAP2K6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).