HIV Target gene Detail Information

> MAP2K4 Gene Search Result


Gene Information
Gene Name MAP2K4
Gene ID 6416
Gene Full Name mitogen-activated protein kinase kinase 4
Gene Alias JNKK; MEK4; MKK4; SEK1; SKK1; JNKK1; SERK1; MAPKK4; PRKMK4; SAPKK1; SAPKK-1
Transcripts ENSG00000065559
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cell Junctions;
HPA Protein Class Info Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID P45985
HGNC ID HGNC:6844
VEGA ID OTTHUMG00000178267
OMIM ID 601335
String ID 9606.ENSP00000410402
Drug (Cytoscape Annotation) Sunitinib Malate;Pazopanib Hydrochloride
PharmGKB ID PA30589
Target gene [MAP2K4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002103 chr17 111 1 112 View
4004271 chr17 18 28 46 View
4008339 chr17 13 2 15 View
4010796 chr17 2 6 8 View

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).