HTLV1 Target gene Detail Information

> MAP2K1 Gene Search Result

Gene Information

Gene Name	MAP2K1
Gene ID	5604
Gene Full Name	mitogen-activated protein kinase kinase 1
Gene Alias	CFC3; MEK1; MKK1; MAPKK1; PRKMK1
Transcripts	ENSG00000169032
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID	Q02750
HGNC ID	HGNC:6840
VEGA ID	OTTHUMG00000133196
OMIM ID	176872
String ID	9606.ENSP00000302486
Drugbank ID	BE0000870
Drug (Cytoscape Annotation)	Trametinib;Cobimetinib;Sunitinib Malate;Bosutinib;Dasatinib
PharmGKB ID	PA30584
FDA Approved Drug	Binimetinib

Target gene [MAP2K1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6004980	chr15	19	78	2	99	View
6020265	chr15	3	4		7	View

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).