HBV Target gene Detail Information

> MANBA Gene Search Result

Gene Information

Gene Name	MANBA
Gene ID	4126
Gene Full Name	mannosidase beta
Gene Alias	MANB1
Transcripts	ENSG00000109323
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	O00462
HGNC ID	HGNC:6831
VEGA ID	OTTHUMG00000131123
OMIM ID	609489
String ID	9606.ENSP00000226578
PharmGKB ID	PA30577

Target gene [MANBA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003422	chr4	11	102	22	135	View
1019881	chr4				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of MANBA expression and immune infiltrating cell level correlation result in HBV+ samples
MANBA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).