HBV Target gene Detail Information

> MAN2A1 Gene Search Result

Gene Information

Gene Name	MAN2A1
Gene ID	4124
Gene Full Name	mannosidase alpha class 2A member 1
Gene Alias	MANA2; MANII; GOLIM7; AMan II
Transcripts	ENSG00000112893
Virus	HBV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted membrane proteins
Uniport_ID	Q16706
HGNC ID	HGNC:6824
VEGA ID	OTTHUMG00000162834
OMIM ID	154582
String ID	9606.ENSP00000261483
Drugbank ID	BE0003505
PharmGKB ID	PA30573

Target gene [MAN2A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005166	chr5	48	12		60	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of MAN2A1 expression and immune infiltrating cell level correlation result in HBV+ samples
MAN2A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).