HBV Target gene Detail Information

> MAN1A1 Gene Search Result


Gene Information
Gene Name MAN1A1
Gene ID 4121
Gene Full Name mannosidase alpha class 1A member 1
Gene Alias MAN9; HUMM3; HUMM9
Transcripts ENSG00000111885
Virus HBV
Gene Type protein coding
HPA Location Info Golgi apparatus;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Plasma proteins, Predicted membrane proteins
Uniport_ID P33908
HGNC ID HGNC:6821
VEGA ID OTTHUMG00000015472
OMIM ID 604344
String ID 9606.ENSP00000357453
PharmGKB ID PA30570
Target gene [MAN1A1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001761 chr6 467 13 17 497 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MAN1A1 expression and immune infiltrating cell level correlation result in HBV+ samples
MAN1A1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).