HBV Target gene Detail Information

> MAGI1 Gene Search Result


Gene Information
Gene Name MAGI1
Gene ID 9223
Gene Full Name membrane associated guanylate kinase, WW and PDZ domain containing 1
Gene Alias AIP3; BAP1; WWP3; AIP-3; BAP-1; BAIAP1; MAGI-1; Magi1d; TNRC19
Transcripts ENSG00000282956
Virus HBV
Gene Type protein coding
HPA Location Info Cell Junctions;Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q96QZ7
HGNC ID HGNC:946
VEGA ID OTTHUMG00000157554
OMIM ID 602625
String ID 9606.ENSP00000385450
PharmGKB ID PA164742006
Target gene [MAGI1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1012460 chr3 6 1 7 View
1012968 chr3 3 3 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MAGI1 expression and immune infiltrating cell level correlation result in HBV+ samples
MAGI1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).