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HPV Target gene Detail Information

> MAFA Gene Search Result


Gene Information
Gene Name MAFA
Gene ID 389692
Gene Full Name MAF bZIP transcription factor A
Gene Alias INSDM; hMafA; RIPE3b1
Transcripts ENSG00000182759
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Gene Function Oncogene
Uniport_ID Q8NHW3
HGNC ID HGNC:23145
VEGA ID OTTHUMG00000165037
OMIM ID 610303
String ID 9606.ENSP00000328364
PharmGKB ID PA134963361
Target gene [MAFA] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5000156 chr8 892 298 133 1323 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE40774 (GEO) Head and neck squamous cell carcinoma 134 Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of MAFA expression and immune infiltrating cell level correlation result in HPV+ samples
MAFA expression: Low -> High

> Dataset: GSE40774

HeatMap of cell type fractions in all samples Lollipop of MAFA expression and immune infiltrating cell level correlation result in HPV+ samples
MAFA expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of MAFA expression and immune infiltrating cell level correlation result in HPV+ samples
MAFA expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of MAFA expression and immune infiltrating cell level correlation result in HPV+ samples
MAFA expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of MAFA expression and immune infiltrating cell level correlation result in HPV+ samples
MAFA expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of MAFA expression and immune infiltrating cell level correlation result in HPV+ samples
MAFA expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of MAFA expression and immune infiltrating cell level correlation result in HPV+ samples
MAFA expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of MAFA expression and immune infiltrating cell level correlation result in HPV+ samples
MAFA expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).