HIV Target gene Detail Information

> LY9 Gene Search Result


Gene Information
Gene Name LY9
Gene ID 4063
Gene Full Name lymphocyte antigen 9
Gene Alias hly9; mLY9; CD229; SLAMF3
Transcripts ENSG00000122224
Virus HIV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info CD markers, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q9HBG7
HGNC ID HGNC:6730
VEGA ID OTTHUMG00000024007
OMIM ID 600684
String ID 9606.ENSP00000263285
PharmGKB ID PA30494
Target gene [LY9] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002121 chr1 93 18 1 112 View
4002540 chr1 11 30 49 90 View
4003248 chr1 55 10 65 View
4015573 chr1 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of LY9 expression and immune infiltrating cell level correlation result in HIV+ samples
LY9 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of LY9 expression and immune infiltrating cell level correlation result in HIV+ samples
LY9 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).