HTLV1 Target gene Detail Information

> LY75 Gene Search Result

Gene Information

Gene Name	LY75
Gene ID	4065
Gene Full Name	lymphocyte antigen 75
Gene Alias	CD205; LY-75; CLEC13B; DEC-205; GP200-MR6
Transcripts	ENSG00000054219
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Predicted membrane proteins
Uniport_ID	O60449
HGNC ID	HGNC:6729
VEGA ID	OTTHUMG00000132025
OMIM ID	604524
String ID	9606.ENSP00000263636
PharmGKB ID	PA30493

Target gene [LY75] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6008524	chr2	15	23	6	44	View
6010209	chr2	7	1	24	32	View
6012441	chr2	21		1	22	View
6015992	chr2	12	1		13	View
6026730	chr2	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of LY75 expression and immune infiltrating cell level correlation result in HTLV1+ samples
LY75 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of LY75 expression and immune infiltrating cell level correlation result in HTLV1+ samples
LY75 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of LY75 expression and immune infiltrating cell level correlation result in HTLV1+ samples
LY75 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).