HBV Target gene Detail Information

> LY6E Gene Search Result

Gene Information

Gene Name	LY6E
Gene ID	4061
Gene Full Name	lymphocyte antigen 6 family member E
Gene Alias	RIGE; SCA2; RIG-E; SCA-2; TSA-1
Transcripts	ENSG00000278032
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q16553
HGNC ID	HGNC:6727
VEGA ID	OTTHUMG00000190650
OMIM ID	601384
String ID	9606.ENSP00000428572
PharmGKB ID	PA30491

Target gene [LY6E] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003900	chr8	79	24		103	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of LY6E expression and immune infiltrating cell level correlation result in HBV+ samples
LY6E expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).