HBV Target gene Detail Information

> LXN Gene Search Result

Gene Information

Gene Name	LXN
Gene ID	56925
Gene Full Name	latexin
Gene Alias	ECI; TCI
Transcripts	ENSG00000079257
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q9BS40
HGNC ID	HGNC:13347
VEGA ID	OTTHUMG00000158807
OMIM ID	609305
String ID	9606.ENSP00000264265
PharmGKB ID	PA134991999

Target gene [LXN] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000147	chr3	3302	936	1090	5328	View
1000148	chr3	3302	936	1090	5328	View
1000149	chr3	3302	936	1090	5328	View
1000150	chr3	3302	936	1090	5328	View
1000153	chr3	3300	931	1080	5311	View
1000154	chr3	3300	931	1080	5311	View
1000155	chr3	3301	927	1077	5305	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of LXN expression and immune infiltrating cell level correlation result in HBV+ samples
LXN expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).