HPV Target gene Detail Information

> LVRN Gene Search Result

Gene Information

Gene Name	LVRN
Gene ID	206338
Gene Full Name	laeverin
Gene Alias	APQ; AQPEP; TAQPEP
Transcripts	ENSG00000172901
Virus	HPV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q6Q4G3
HGNC ID	HGNC:26904
VEGA ID	OTTHUMG00000128890
OMIM ID	610046
PharmGKB ID	PA166181553

Target gene [LVRN] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5002548	chr5	9	1		10	View
5403090	chr5	35	2		37	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE65858 (GEO)	Head and neck squamous cell carcinoma	270	Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE51993 (GEO)	Cervical intraepithelial neoplasia	24	Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)

> Dataset: GSE65858
HeatMap of cell type fractions in all samples	Lollipop of LVRN expression and immune infiltrating cell level correlation result in HPV+ samples
LVRN expression: Low -> High

> Dataset: GSE51993
HeatMap of cell type fractions in all samples	Lollipop of LVRN expression and immune infiltrating cell level correlation result in HPV+ samples
LVRN expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).