HBV Target gene Detail Information

> LSS Gene Search Result

Gene Information

Gene Name	LSS
Gene ID	4047
Gene Full Name	lanosterol synthase
Gene Alias	OSC; CTRCT44
Transcripts	ENSG00000281289
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P48449
HGNC ID	HGNC:6708
VEGA ID	OTTHUMG00000189937
OMIM ID	600909
String ID	9606.ENSP00000380837
Drugbank ID	BE0001466
PharmGKB ID	PA30473

Target gene [LSS] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000427	chr21	2174	114	62	2350	View
1403898	chr21	2174	114	62	2350	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of LSS expression and immune infiltrating cell level correlation result in HBV+ samples
LSS expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).