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HTLV1 Target gene Detail Information

> LSM5 Gene Search Result


Gene Information
Gene Name LSM5
Gene ID 23658
Gene Full Name LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
Gene Alias YER146W
Transcripts ENSG00000106355
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9Y4Y9
HGNC ID HGNC:17162
VEGA ID OTTHUMG00000022913
OMIM ID 607285
String ID 9606.ENSP00000410758
PharmGKB ID PA134881171
Target gene [LSM5] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6030392 chr7 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of LSM5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
LSM5 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of LSM5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
LSM5 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of LSM5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
LSM5 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).