HIV Target gene Detail Information

> LSM2 Gene Search Result

Gene Information

Gene Name	LSM2
Gene ID	57819
Gene Full Name	LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
Gene Alias	G7B; snRNP; C6orf28; YBL026W
Transcripts	ENSG00000236826
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9Y333
HGNC ID	HGNC:13940
VEGA ID	OTTHUMG00000149939
OMIM ID	607282
String ID	9606.ENSP00000364813
PharmGKB ID	PA25929

Target gene [LSM2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013217	chr6	2	2		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of LSM2 expression and immune infiltrating cell level correlation result in HIV+ samples
LSM2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of LSM2 expression and immune infiltrating cell level correlation result in HIV+ samples
LSM2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).