HPV Target gene Detail Information

> LSM11 Gene Search Result


Gene Information
Gene Name LSM11
Gene ID 134353
Gene Full Name LSM11, U7 small nuclear RNA associated
Transcripts ENSG00000155858
Virus HPV
Gene Type protein coding
HPA Location Info Nucleoplasm;Nuclear bodies;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID P83369
HGNC ID HGNC:30860
VEGA ID OTTHUMG00000130255
OMIM ID 617910
String ID 9606.ENSP00000286307
PharmGKB ID PA134983181
Target gene [LSM11] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5000734 chr5 86 7 93 View
5200229 chr5 30 30 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE138080 (GEO) Cervical intraepithelial neoplasia 25 Normal (10), Cervical intraepithelial neoplasia (HPV+)(15)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of LSM11 expression and immune infiltrating cell level correlation result in HPV+ samples
LSM11 expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of LSM11 expression and immune infiltrating cell level correlation result in HPV+ samples
LSM11 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of LSM11 expression and immune infiltrating cell level correlation result in HPV+ samples
LSM11 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of LSM11 expression and immune infiltrating cell level correlation result in HPV+ samples
LSM11 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of LSM11 expression and immune infiltrating cell level correlation result in HPV+ samples
LSM11 expression: Low -> High

> Dataset: GSE138080

HeatMap of cell type fractions in all samples Lollipop of LSM11 expression and immune infiltrating cell level correlation result in HPV+ samples
LSM11 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of LSM11 expression and immune infiltrating cell level correlation result in HPV+ samples
LSM11 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of LSM11 expression and immune infiltrating cell level correlation result in HPV+ samples
LSM11 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).