HIV Target gene Detail Information

> LRTOMT Gene Search Result

Gene Information

Gene Name	LRTOMT
Gene ID	220074
Gene Full Name	leucine rich transmembrane and O-methyltransferase domain containing
Gene Alias	DFNB63; LRRC51; CFAP111
Transcripts	ENSG00000184154
Virus	HIV
Gene Type	protein coding
HPA Location Info	Microtubules;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q8WZ04; Q96E66
HGNC ID	HGNC:25033
VEGA ID	OTTHUMG00000154887
OMIM ID	612414
String ID	9606.ENSP00000305742
PharmGKB ID	PA164722133

Target gene [LRTOMT] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010272	chr11	5	3	1	9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of LRTOMT expression and immune infiltrating cell level correlation result in HIV+ samples
LRTOMT expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).