HBV Target gene Detail Information

> LRRTM4 Gene Search Result

Gene Information

Gene Name	LRRTM4
Gene ID	80059
Gene Full Name	leucine rich repeat transmembrane neuronal 4
Transcripts	ENSG00000176204
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q86VH4
HGNC ID	HGNC:19411
VEGA ID	OTTHUMG00000152842
OMIM ID	610870
String ID	9606.ENSP00000386357
PharmGKB ID	PA134972631

Target gene [LRRTM4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1016479	chr2		1		1	View
1017181	chr2	1			1	View
1017182	chr2		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of LRRTM4 expression and immune infiltrating cell level correlation result in HBV+ samples
LRRTM4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).