HTLV1 Target gene Detail Information

> LRRN4 Gene Search Result

Gene Information

Gene Name	LRRN4
Gene ID	164312
Gene Full Name	leucine rich repeat neuronal 4
Gene Alias	NLRR4; NLRR-4; C20orf75; dJ1056H1.1
Transcripts	ENSG00000125872
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Mitotic chromosome;Nucleoli;Nucleoli rim;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q8WUT4
HGNC ID	HGNC:16208
VEGA ID	OTTHUMG00000031825
String ID	9606.ENSP00000368135
PharmGKB ID	PA162394670

Target gene [LRRN4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000441	chr20	1297	158	140	1595	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of LRRN4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
LRRN4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).