HPV Target gene Detail Information

> LRRC72 Gene Search Result


Gene Information
Gene Name LRRC72
Gene ID 100506049
Gene Full Name leucine rich repeat containing 72
Transcripts ENSG00000205858
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID A6NJI9
HGNC ID HGNC:42972
VEGA ID OTTHUMG00000152446
String ID 9606.ENSP00000384971
PharmGKB ID PA166049094
Target gene [LRRC72] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5002855 chr7 4 3 7 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of LRRC72 expression and immune infiltrating cell level correlation result in HPV+ samples
LRRC72 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of LRRC72 expression and immune infiltrating cell level correlation result in HPV+ samples
LRRC72 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of LRRC72 expression and immune infiltrating cell level correlation result in HPV+ samples
LRRC72 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of LRRC72 expression and immune infiltrating cell level correlation result in HPV+ samples
LRRC72 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).