HTLV1 Target gene Detail Information

> LRRC69 Gene Search Result

Gene Information

Gene Name	LRRC69
Gene ID	100130742
Gene Full Name	leucine rich repeat containing 69
Transcripts	ENSG00000214954
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q6ZNQ3
HGNC ID	HGNC:34303
VEGA ID	OTTHUMG00000164023
String ID	9606.ENSP00000400803
PharmGKB ID	PA162394619

Target gene [LRRC69] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6029761	chr8	1			1	View
6029762	chr8	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of LRRC69 expression and immune infiltrating cell level correlation result in HTLV1+ samples
LRRC69 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).