HTLV1 Target gene Detail Information

> LRRC63 Gene Search Result


Gene Information
Gene Name LRRC63
Gene ID 220416
Gene Full Name leucine rich repeat containing 63
Transcripts ENSG00000173988
Virus HTLV1
Gene Type protein coding
HPA Location Info Golgi apparatus;
HPA Protein Class Info Predicted intracellular proteins
HGNC ID HGNC:34296
VEGA ID OTTHUMG00000016866
String ID 9606.ENSP00000469337
PharmGKB ID PA162394565
Target gene [LRRC63] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6016775 chr13 9 3 12 View
6019826 chr13 6 1 7 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of LRRC63 expression and immune infiltrating cell level correlation result in HTLV1+ samples
LRRC63 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).