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HBV Target gene Detail Information

> LRRC4C Gene Search Result


Gene Information
Gene Name LRRC4C
Gene ID 57689
Gene Full Name leucine rich repeat containing 4C
Gene Alias NGL1; NGL-1
Transcripts ENSG00000148948
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q9HCJ2
HGNC ID HGNC:29317
VEGA ID OTTHUMG00000166383
OMIM ID 608817
String ID 9606.ENSP00000278198
PharmGKB ID PA142671534
Target gene [LRRC4C] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009122 chr11 12 3 2 17 View
1011075 chr11 7 3 10 View
1013152 chr11 4 1 5 View
1014503 chr11 2 1 3 View
1016844 chr11 1 1 View
1018064 chr11 0 View
1400959 chr11 4 1 5 View
1400960 chr11 2 1 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of LRRC4C expression and immune infiltrating cell level correlation result in HBV+ samples
LRRC4C expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).