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HPV Target gene Detail Information

> LRRC3B Gene Search Result


Gene Information
Gene Name LRRC3B
Gene ID 116135
Gene Full Name leucine rich repeat containing 3B
Gene Alias LRP15
Transcripts ENSG00000179796
Virus HPV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Gene Function Suppressor gene
Uniport_ID Q96PB8
HGNC ID HGNC:28105
VEGA ID OTTHUMG00000130572
OMIM ID 618996
String ID 9606.ENSP00000379880
PharmGKB ID PA134962068
Target gene [LRRC3B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5201767 chr3 0 View
5201858 chr3 1 1 View
5402792 chr3 5 5 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of LRRC3B expression and immune infiltrating cell level correlation result in HPV+ samples
LRRC3B expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of LRRC3B expression and immune infiltrating cell level correlation result in HPV+ samples
LRRC3B expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of LRRC3B expression and immune infiltrating cell level correlation result in HPV+ samples
LRRC3B expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of LRRC3B expression and immune infiltrating cell level correlation result in HPV+ samples
LRRC3B expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of LRRC3B expression and immune infiltrating cell level correlation result in HPV+ samples
LRRC3B expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of LRRC3B expression and immune infiltrating cell level correlation result in HPV+ samples
LRRC3B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).