HIV Target gene Detail Information

> LRRC37B Gene Search Result

Gene Information

Gene Name	LRRC37B
Gene ID	114659
Gene Full Name	leucine rich repeat containing 37B
Gene Alias	LRRC37
Transcripts	ENSG00000185158
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q96QE4
HGNC ID	HGNC:29070
VEGA ID	OTTHUMG00000132785
OMIM ID	616558
String ID	9606.ENSP00000340519
PharmGKB ID	PA142671525

Target gene [LRRC37B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4012734	chr17	1	3		4	View
4015631	chr17	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of LRRC37B expression and immune infiltrating cell level correlation result in HIV+ samples
LRRC37B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).