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HBV Target gene Detail Information

> LRPPRC Gene Search Result


Gene Information
Gene Name LRPPRC
Gene ID 10128
Gene Full Name leucine rich pentatricopeptide repeat containing
Gene Alias LSFC; GP130; LRP130; CLONE-23970
Transcripts ENSG00000138095
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID P42704
HGNC ID HGNC:15714
VEGA ID OTTHUMG00000152782
OMIM ID 607544
String ID 9606.ENSP00000260665
PharmGKB ID PA30459
Target gene [LRPPRC] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002251 chr2 52 126 127 305 View
1002419 chr2 55 107 116 278 View
1011039 chr2 9 1 10 View
1401712 chr2 52 126 127 305 View
1401713 chr2 55 107 116 278 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of LRPPRC expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
LRPPRC expression: Low -> High
Lollipop of LRPPRC expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of LRPPRC expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of LRPPRC expression and immune infiltrating cell level correlation result in HBV+ samples
LRPPRC expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).