HBV Target gene Detail Information

> LRP8 Gene Search Result

Gene Information

Gene Name	LRP8
Gene ID	7804
Gene Full Name	LDL receptor related protein 8
Gene Alias	MCI1; LRP-8; APOER2; HSZ75190
Transcripts	ENSG00000157193
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID	Q14114
HGNC ID	HGNC:6700
VEGA ID	OTTHUMG00000008924
OMIM ID	602600
String ID	9606.ENSP00000303634
PharmGKB ID	PA30457

Target gene [LRP8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1015808	chr1	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of LRP8 expression and immune infiltrating cell level correlation result in HBV+ samples
LRP8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).