HIV Target gene Detail Information

> LRP4 Gene Search Result

Gene Information

Gene Name	LRP4
Gene ID	4038
Gene Full Name	LDL receptor related protein 4
Gene Alias	CLSS; CMS17; LRP-4; LRP10; MEGF7; SOST2
Transcripts	ENSG00000134569
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;Nucleoli;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O75096
HGNC ID	HGNC:6696
VEGA ID	OTTHUMG00000166700
OMIM ID	604270
String ID	9606.ENSP00000367888
PharmGKB ID	PA30454

Target gene [LRP4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4012197	chr11	4	1		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of LRP4 expression and immune infiltrating cell level correlation result in HIV+ samples
LRP4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).