HBV Target gene Detail Information

> LRP2 Gene Search Result

Gene Information

Gene Name	LRP2
Gene ID	4036
Gene Full Name	LDL receptor related protein 2
Gene Alias	DBS; GP330; LRP-2
Transcripts	ENSG00000081479
Virus	HBV
Gene Type	protein coding
HPA Location Info	Mitochondria;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	P98164
HGNC ID	HGNC:6694
VEGA ID	OTTHUMG00000132179
OMIM ID	600073
String ID	9606.ENSP00000263816
Drugbank ID	BE0000942
PharmGKB ID	PA30452

Target gene [LRP2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002216	chr2	230	79	4	313	View
1002248	chr2	217	85	4	306	View
1002898	chr2	12	128	53	193	View
1402728	chr2	230	79	4	313	View
1402729	chr2	217	85	4	306	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of LRP2 expression and immune infiltrating cell level correlation result in HBV+ samples
LRP2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).