HBV Target gene Detail Information

> LRP1B Gene Search Result

Gene Information

Gene Name	LRP1B
Gene ID	53353
Gene Full Name	LDL receptor related protein 1B
Gene Alias	LRP-1B; LRPDIT; LRP-DIT
Transcripts	ENSG00000168702
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Suppressor gene
Uniport_ID	Q9NZR2
HGNC ID	HGNC:6693
VEGA ID	OTTHUMG00000131799
OMIM ID	608766
String ID	9606.ENSP00000374135
PharmGKB ID	PA30451

Target gene [LRP1B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005236	chr2	5	21	32	58	View
1005237	chr2	4	22	32	58	View
1005379	chr2	1	30	24	55	View
1006604	chr2	36			36	View
1006849	chr2	33			33	View
1012917	chr2	5	1		6	View
1014233	chr2	1		3	4	View
1014339	chr2	2		1	3	View
1403724	chr2		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of LRP1B expression and immune infiltrating cell level correlation result in HBV+ samples
LRP1B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).