HBV Target gene Detail Information

> LRFN2 Gene Search Result

Gene Information

Gene Name	LRFN2
Gene ID	57497
Gene Full Name	leucine rich repeat and fibronectin type III domain containing 2
Gene Alias	SALM1; FIGLER2; KIAA1246
Transcripts	ENSG00000156564
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q9ULH4
HGNC ID	HGNC:21226
VEGA ID	OTTHUMG00000014662
OMIM ID	612808
String ID	9606.ENSP00000345985
PharmGKB ID	PA134913285

Target gene [LRFN2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005294	chr6	18	10	29	57	View
1006190	chr6	38	2	2	42	View
1006792	chr6	29	4	1	34	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of LRFN2 expression and immune infiltrating cell level correlation result in HBV+ samples
LRFN2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).