HIV Target gene Detail Information

> LRCH1 Gene Search Result


Gene Information
Gene Name LRCH1
Gene ID 23143
Gene Full Name leucine rich repeats and calponin homology domain containing 1
Gene Alias NP81; CHDC1
Transcripts ENSG00000136141
Virus HIV
Gene Type protein coding
HPA Location Info Actin filaments;Cytosol;Nucleoli;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q9Y2L9
HGNC ID HGNC:20309
VEGA ID OTTHUMG00000016877
OMIM ID 610368
String ID 9606.ENSP00000374447
PharmGKB ID PA134898200
Target gene [LRCH1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4003896 chr13 46 2 4 52 View
4008600 chr13 12 2 14 View
4011700 chr13 5 1 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of LRCH1 expression and immune infiltrating cell level correlation result in HIV+ samples
LRCH1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).