HIV Target gene Detail Information

> LRCH1 Gene Search Result

Gene Information

Gene Name	LRCH1
Gene ID	23143
Gene Full Name	leucine rich repeats and calponin homology domain containing 1
Gene Alias	NP81; CHDC1
Transcripts	ENSG00000136141
Virus	HIV
Gene Type	protein coding
HPA Location Info	Actin filaments;Cytosol;Nucleoli;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9Y2L9
HGNC ID	HGNC:20309
VEGA ID	OTTHUMG00000016877
OMIM ID	610368
String ID	9606.ENSP00000374447
PharmGKB ID	PA134898200

Target gene [LRCH1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003896	chr13	46	2	4	52	View
4008600	chr13	12		2	14	View
4011700	chr13	5	1		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of LRCH1 expression and immune infiltrating cell level correlation result in HIV+ samples
LRCH1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).