Home
Virus
Gene
Disease
Dataset
Download
Help
 
HTLV1 Target gene Detail Information

> LOXL3 Gene Search Result


Gene Information
Gene Name LOXL3
Gene ID 84695
Gene Full Name lysyl oxidase like 3
Gene Alias LOXL
Transcripts ENSG00000115318
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P58215
HGNC ID HGNC:13869
VEGA ID OTTHUMG00000129953
OMIM ID 607163
String ID 9606.ENSP00000264094
PharmGKB ID PA30430
Target gene [LOXL3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6005494 chr2 49 29 8 86 View
6005813 chr2 47 26 7 80 View
6022379 chr2 4 1 5 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of LOXL3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
LOXL3 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of LOXL3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
LOXL3 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of LOXL3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
LOXL3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).