HBV Target gene Detail Information

> LONP1 Gene Search Result

Gene Information

Gene Name	LONP1
Gene ID	9361
Gene Full Name	lon peptidase 1, mitochondrial
Gene Alias	LON; LONP; PIM1; hLON; LonHS; CODASS; PRSS15
Transcripts	ENSG00000196365
Virus	HBV
Gene Type	protein coding
HPA Location Info	Mitochondria;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P36776
HGNC ID	HGNC:9479
VEGA ID	OTTHUMG00000180504
OMIM ID	605490
String ID	9606.ENSP00000353826
PharmGKB ID	PA162394145

Target gene [LONP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007181	chr19	14	15		29	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of LONP1 expression and immune infiltrating cell level correlation result in HBV+ samples
LONP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).