HIV Target gene Detail Information

> LOC374443 Gene Search Result

Gene Information

Gene Name	LOC374443
Gene ID	374443
Gene Full Name	C-type lectin domain family 2 member D pseudogene
Transcripts	ENSG00000256594
Virus	HIV
Gene Type	pseudo
HPA Location Info

Target gene [LOC374443] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003843	chr12	50	3		53	View
4007183	chr12	20			20	View
4009321	chr12	9	3		12	View
4013147	chr12	2		2	4	View
4014350	chr12	1		1	2	View
4015597	chr12	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of LOC374443 expression and immune infiltrating cell level correlation result in HIV+ samples
LOC374443 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of LOC374443 expression and immune infiltrating cell level correlation result in HIV+ samples
LOC374443 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).