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HPV Target gene Detail Information

> LIPC Gene Search Result


Gene Information
Gene Name LIPC
Gene ID 3990
Gene Full Name lipase C, hepatic type
Gene Alias HL; HTGL; LIPH; HDLCQ12
Transcripts ENSG00000166035
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins
Uniport_ID P11150
HGNC ID HGNC:6619
VEGA ID OTTHUMG00000132632
OMIM ID 151670
String ID 9606.ENSP00000299022
PharmGKB ID PA230
Target gene [LIPC] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5001900 chr15 7 7 6 20 View
5300324 chr15 324 376 179 879 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of LIPC expression and immune infiltrating cell level correlation result in HPV+ samples
LIPC expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of LIPC expression and immune infiltrating cell level correlation result in HPV+ samples
LIPC expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of LIPC expression and immune infiltrating cell level correlation result in HPV+ samples
LIPC expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of LIPC expression and immune infiltrating cell level correlation result in HPV+ samples
LIPC expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of LIPC expression and immune infiltrating cell level correlation result in HPV+ samples
LIPC expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of LIPC expression and immune infiltrating cell level correlation result in HPV+ samples
LIPC expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of LIPC expression and immune infiltrating cell level correlation result in HPV+ samples
LIPC expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).