HBV Target gene Detail Information

> LIPA Gene Search Result

Gene Information

Gene Name	LIPA
Gene ID	3988
Gene Full Name	lipase A, lysosomal acid type
Gene Alias	LAL; CESD
Transcripts	ENSG00000107798
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Vesicles;Nucleoli fibrillar center;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P38571
HGNC ID	HGNC:6617
VEGA ID	OTTHUMG00000018716
OMIM ID	613497
String ID	9606.ENSP00000337354
Drugbank ID	BE0003764
PharmGKB ID	PA30391

Target gene [LIPA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001156	chr10	737	80	168	985	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of LIPA expression and immune infiltrating cell level correlation result in HBV+ samples
LIPA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).