HTLV1 Target gene Detail Information

> LINGO3 Gene Search Result

Gene Information

Gene Name	LINGO3
Gene ID	645191
Gene Full Name	leucine rich repeat and Ig domain containing 3
Gene Alias	LERN2; LRRN6B
Transcripts	ENSG00000220008
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Mitochondria;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	P0C6S8
HGNC ID	HGNC:21206
VEGA ID	OTTHUMG00000180418
OMIM ID	609792
String ID	9606.ENSP00000467753
PharmGKB ID	PA162394097

Target gene [LINGO3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6017860	chr19	3	4	3	10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of LINGO3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
LINGO3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).